negative response of phytoestrogens of pomegranate flower extract against cisplatin‑induced nephrotoxicity in female rats
نویسندگان
چکیده
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منابع مشابه
Pomegranate Flower Extract does not Prevent Cisplatin-Induced Nephrotoxicity in Female Rats
BACKGROUND Nephrotoxicity is the major side-effect of cisplatin (CDDP), and it is reported to be gender-related. We evaluated the effects of pomegranate flower extract (PFE) as an antioxidant on CDDP-induced nephrotoxicity in female rats. METHODS Twenty-three adult female rats in four groups treated as following. Groups 1 and 2 received PFE at doses of 25 and 50 (mg/kg/day), respectively, for...
متن کاملEffect of pomegranate flower extract on cisplatin-induced nephrotoxicity in rats
BACKGROUND Chemotherapy with cisplatin (CP) is accompanied with nephrotoxicity. OBJECTIVES In the current study, pomegranate flower extract (PFE) has been evaluated as an antioxidant agent against CP-induced-renal toxicity. MATERIALS AND METHODS Thirty two male Wistar rats were divided into five groups (6-8 in each group). The animals in groups 1 to 3 received PFE (25 mg/kg), PFE (50 mg/kg)...
متن کاملComment on: effect of pomegranate flower extract oncis platin-induced nephrotoxicity in rats
Implication for health policy/practice/research/medical education: Antioxidant supplements have generally beneficial effects, however, several factors such as the kind of the antioxidant and the dose should be considered to avoid the potential negative effects. Dear editor We read with respect the paper " effect of pomegranate flower extract on cisplatin-induced nephrotoxicity in rats " by Mota...
متن کاملpomegranate flower extract does not prevent cisplatin-induced nephrotoxicity in female rats
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چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولProtective effect of pomegranate flower extract against gentamicin-induced renal toxicity in male rats
INTRODUCTION Gentamicin (GM) as an antibiotic is used in clinic. However, its administration is limited by side effects such as nephrotoxicity. Herbal extracts could be used in therapeutic approaches. OBJECTIVES The present study was planned to investigate whether pomegranate flower extract (PFE) could ameliorate GM-induced renal toxicity in male rats. MATERIALS AND METHODS Twenty eight mal...
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عنوان ژورنال:
international journal of preventive medicineجلد ۲۰۱۶، شماره ۰۶، صفحات ۰-۰
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